$10,000 Dollar Bill. Yes it is real. The Federal Reserve used it to transfer money to and from banks and was never issued to the public. They also produced a $500, $1,000, $5,000 and even a $100,000 dollar note, see below. They were last printed in 1945 and have since been discontinued.

$100,000 Dollar Note. This is the 1934 $100,000 dollar note. It featured Woodrow Wilson.