Sam Harris
Sameer A. Sheth, MD, PhD
Mark S. Cohen, PhD

Objective: The difference between believing and disbelieving a proposition is one of the most potent regulators of human behavior and emotion. When we accept a statement as true, it becomes the basis for further thought and action; rejected as false, it remains a string of words. The purpose of this study was to differentiate belief, disbelief, and uncertainty at the level of the brain.