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Generic Name: entacapone (en TAH cah pone)
Brand Names: Comtan

What is entacapone?

When used with levodopa and carbidopa, entacapone increases levels of levodopa (Dopar, Larodopa, Sinemet) in the body.

Entacapone is used with carbidopa and levodopa to treat patients with Parkinson's disease who experience the signs and symptoms of end-of-dose "wearing-off". Entacapone is used only in combination with carbidopa and levodopa. It has no effect if it is used on its own.

Entacapone may also be used for purposes other than those listed in the medication guide.